Adventures with Bruce Ames and the Ames test

Ames, the Ames test, and the causes of cancer.

Mutagenicity of glutathione and cysteine in the Ames test.

Postmitochondrial supernatant from rat liver and kidney homogenates transformed cysteine into a mutagen that reverted bacteria of the strain Salmonella typhimurium TA100 to histidine independence. Glutathione was also activated by kidney postmitochondrial supernatant but not by liver preparations. Hence, important endogenous compounds of mammals are positive in the most commonly used short-term...

Field Experiments with the Ames Marsokhod Rover

In an ongoing series of field experiments, the Ames Marsokhod rover is deployed to remote locations and operated by scientists in simulated planetary explorations. These experiments provide insight both for scientists preparing for real planetary surface exploration and for robotics researchers. In this paper we will provide an overview of our work with the Marsokhod, describe the various subsy...

Antimutagenic activity of Chloroformic and Methanolic extracts of muscle, liver and cartilage of Sphyrna lewini with the Ames test

  For this study one species of Shyrnidae family caught along Persian Gulf in Bandarabbas city. Sphyrna lewini were transferred to the laboratory on spring 2007. The antimutagenic activity of the Methanolic and Chloroforamic extracts of muscle, liver and cartilage of Sphyrna lewini with the Ames test was investigated. The use of antimutagens and anticarcinogens in everyday life is the most effe...

Evaluation of the Ames "Seralyzer".

Analyte Control I Control II Control I Control II Sodium 0.9(117.7) 1.2(142.7) 1.1(118.7) 1.2(142.0) Potassium 1.1(4.18) 1.3(6.1) 1.1(4.23) 0.9(6.60) Glucose 1.8(6.29) 2.1(14.87) 1.4(4.98) 0.9(14.51) Amylase 4.7(38.1) 6.1(113) 4.5(36.6) 3.9(121.3) Creatinine 19.4(70.4) 5.4(478.9) 24.9(63.2) 3.5(453.3) Bilirubin 3.4(22.2) 1.1(87.9) 4.1(22.3) 1.3(87.3) Urate 1.4(270.9) 1.4(512.7) 0.9(262.9) 0.9(4...